Discussion
Diagnosis With Brief Discussion
- Diagnosis
- Wegener's granulomatosis
- Radiologic Findings
- Figure 1. Chest radiograph shows multiple patchy nodular opacities in both lungs.
Figure 2. Water`s view shows mucoperiosteal thickening in both maxillary sinuses.
Figure 3-5. Chest CT scan shows multiple, irregular or ill-defined nodules scattered in both lungs with peribronchovascular or centrilobular distribution pattern.
- Brief Review
- In this case, thoracoscopic wedge resection in the left lower lobe was done and the specimen revealed capillaritis and fibrinoid necrosis with cicatrical change in arterioles and venules. Laboratory test show all positive for c-ANCA ( MPO Ab) and p-ANCA ( PR3-Ab ). Wegener’s granulomatosis was diagnosed in consideration of his radiologic, pathologic and clinical findings. After steroid and cytoxan treatment, three months follow up chest radiograph (not shown) showed disappearance of the nodular opacities scattered in both lungs.
- References
- Please refer to case 90, 104.
- Keywords
- Lung, Vasculitis, ANCA associated vasculitis,